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The canine infectious respiratory disease complex (CIRDC) is a globally endemic syndrome involving multiple viral and bacterial pathogens. It is characterized by the abrupt onset of a dry cough, often intense, sometimes accompanied by expectoration and nasal-ocular discharge. CIRDC can affect dogs of all ages and is typically prevalent in environments where large numbers of dogs are housed together (such as kennels or boarding facilities) or in locations where dog shows and training classes are conducted. This stu...

The infectious diseases are mainly the consequence of the existence of the microbialworld, essential for life on our planet. Microbes need a superior animal to multiply andspread to survive. The pathogens are therefore the biological agents responsible for theonset of the disease condition in the host organism. The infectious disease appears to bethe consequence of the interaction between pathogens and specific defense systems,immune response, and nonspecific (inflammation) of the host.West Nile virus (WNV) belong...